src: cjasn.asnjournals.org
Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA. The condition has been first described by Paul Kaznelson in 1922.
Video Pure red cell aplasia
Symptoms
Symptoms can include:
- pallor
- tachycardia
- decreased activity
Maps Pure red cell aplasia
Causes
Causes of PRCA include:
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Treatment
PRCA is considered an autoimmune disease as it will respond to immunosuppressant treatment such as ciclosporin in many patients, though this approach is not without risk.
It has also been shown to respond to treatments with Rituximab and Tacrolimus.
src: www.bloodjournal.org
See also
- Diamond-Blackfan anemia (genetic red cell aplasia)
- Aplastic anemia (aplasia affecting other bone marrow cells as well)
src: www.bloodjournal.org
References
src: esmoopen.bmj.com
External links
- Aplastic Anemia & MDS International Foundation
Source of the article : Wikipedia